College football expert picks, predictions, best bets for Week 1, 2021: Texas vs. Louisiana goes over 58

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After a delayed start last season, college football is back with its more traditional showcase over Labor Day Weekend. The Week 1 college football odds board is loaded up with big slates on Thursday, Friday and Saturday. There are also standalone matchups on both Sunday and Monday. Clemson vs. Georgia is the headliner on Saturday, and Caesars Sportsbook lists the Tigers as three-point favorites. 

Notre Dame is -7.5 against Florida State on Sunday. Lane Kiffin and Ole Miss have the 10-point edge over Louisville, according to the latest Week 1 college football lines, on Monday. Before locking any college football bets for this weekend’s action, be sure to see the top Week 1 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider — a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread — and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past two-plus years, he is 82-55 in his popular best bets column at SportsLine, including going 3-0 to start the 2021 season. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 1 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 1 college football expert predictions

One of Sallee’s top college football picks for Week 1: He’s going over (58) in the Texas vs. Louisiana matchup on Saturday at 4:30 p.m. ET. 

This certainly isn’t a typical early-season matchup of a Power 5 program against a Group of 5 team. The Ragin’ Cajuns come into this matchup ranked No. 23, setting up a Top 25 showdown against new coach Steve Sarkisian and the No. 21 Longhorns. Louisiana brings back more than 90 percent of production from a year ago, including star quarterback Levi Lewis

Texas, meanwhile, really struggled defensively a year ago and Sallee sees troubles on that side of the ball carrying into 2021 under the new staff. Sallee says this game “will be a track meet” that could clear 70 points, making the over the value play. 

Featured Game | Texas Longhorns vs. Louisiana Ragin’ Cajuns

How to make Week 1 college football picks 

Sallee has also found two other college football picks he’s high on, including backing an underdog in a game where he says “the wrong team is favored.” You can only see his picks at SportsLine.

What are the best bets for Week 1 of college football? And which line does Sallee believe is flipped? Visit SportsLine now to see Barrett Sallee’s college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.

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