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The stakes will be high on both sides Sunday when Novak Djokovic and Daniil Medvedev face off in the men’s singles final at the 2021 U.S. Open in New York. The top-ranked and top-seeded Djokovic can win a record 21st major title and his fourth straight Grand Slam by beating No. 2 seed and world No. 2 Medvedev. The Russian is in his third Grand Slam final and will try to close out his first major title. Medvedev has lost just one set in Flushing Meadows, while Djokovic has dropped the first one in each of his past four matches. Djokovic currently shares the record of 20 Grand Slam titles with Roger Federer and Rafael Nadal.
The match at Arthur Ashe Stadium is scheduled for 4 p.m. ET. The latest Djokovic vs. Medvedev odds from Caesars Sportsbook list Djokovic as the -275 favorite (risk $275 to win $100), while Medvedev is the +230 underdog. The over-under for total games is set at 38.5 in the latest 2021 U.S. Open odds. Before you make any Djokovic vs. Medvedev men’s final picks or 2021 U.S. Open predictions, make sure you check out what expert Sean Calvert has to say.
Calvert is the renowned handicapper who called Stan Wawrinka winning the 2014 Australian Open at 60-1, the last Australian title won by someone other than Novak Djokovic or Roger Federer. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1.
And earlier in 2021, he nailed both of his bets for the Wimbledon men’s singles final: Djokovic to beat Matteo Berrettini three sets to one (+275) and Djokovic to win and both players to win a set (+130). Anyone following his picks is way up.
Now, Calvert has been digging deep into the latest 2021 U.S. Open odds and released his best bets for Djokovic vs. Medvedev. He’s only sharing his expert U.S. Open picks and analysis at SportsLine.
Novak Djokovic vs. Daniil Medvedev preview
The pressure will be on both players, and having to rally from a set down in his past four meetings shows it could be getting to Djokovic. But his mental preparation has never been questioned, and he will be laser-focused on making history. Rod Laver, the last man to win all four majors in a calendar year, was in the crowd Friday and is expected to be on hand for the final. The Serb made quick work of Medvedev in Melbourne, winning 7-5, 6-2, 6-2, and he is 5-3 in their all-time meetings. Djokovic’s superb fitness also should be an edge on a hot afternoon.
Medvedev has won three of the past five meetings with Djokovic, including a 6-3, 6-3 victory in November. The 25-year-old went on to beat Rafael Nadal and Dominic Thiem, meaning he swept through the world’s top three players, to win the title at the Nitto ATP Finals in London. He also played a thrilling five-set match with Rafael Nadal in the 2019 U.S. Open final. Djokovic, 34, is as fit as they come, but the 25-year-old Medvedev has the younger and fresher legs. But the experience could make a difference as the Serb mixes things up to keep Medvedev off balance.
How to make Djokovic vs. Medvedev picks
Calvert has broken down the latest U.S. Open men’s final odds and released his coveted Djokovic vs. Medvedev best bet and a full breakdown of the match. He’s locked in value on a wager with a plus-money payout and says you should strongly consider a couple of others. His picks and analysis are only available at SportsLine.
Who wins Medvedev vs. Djokovic in the U.S. Open 2021 men’s final? And what best bet has the most value? Visit SportsLine now to see Sean Calvert’s best bets for Djokovic vs. Medvedev, all from the famed tennis handicapper who called Wawrinka winning the 2014 Australian Open at 60-1, and find out.